The present study was designed to evaluate in vivo efficacy of polyherbal formulation, Himpyrin liquid, for anti-inflammatory, analgesic, and antipyretic activities in cats. Twenty cats with a history of pain, inflammation, and fever due to scratch injuries/ accidents were selected (G1; n = 20) and supplemented with Himpyrin liquid along with standard treatment until complete recovery. The changes in assessment parameters score, viz. pain, fever, and activity level scores, along with adverse effects and product performance/satisfaction scores were evaluated. The results of the present study revealed that pain (p < 0.01) and fever (p < 0.001) were significantly decreased in cats as early as days 2 and 4, respectively, following Himpyrin liquid supplementation along with standard treatment. The administration of Himpyrin liquid to cats restored the activity level of cats affected with fever and pain due to scratch injuries/accidents. Furthermore, Himpyrin liquid was considered highly satisfactory for inflammation amelioration due to scratch injuries/accidents in cats without any adverse effects. In conclusion, this study supplies considerable preliminary data to hint that Himpyrin liquid possesses anti-inflammatory activities. Hence, Himpyrin liquid at 1 mL twice daily along with standard treatment could be recommended for inflammation amelioration and pain in cats. However, further clinical studies evaluating biochemical parameters were recommended to be carried out to better elucidate the mechanism of action and ultimate impact on the overall health of cats.

Highlights

• Himpyrin administration alleviates inflammation and pain in cats and feline.
• Himpyrin liquid possesses anti-inflammatory activities.